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Head-to-head buyer guide

NOVOS NOVOS Core vs Tru Niagen Tru Niagen (300mg NIAGEN)

Specs, prices, editor verdict, and who should buy which — compared side-by-side.

By Ryan · Editor & Founder
Published May 3, 2026
NOVOS Core 12-ingredient daily longevity supplement packet box
NOVOS

NOVOS Core

The longevity stack with a Harvard / MIT scientific board behind it — twelve ingredients in one daily packet, designed to address what the team calls "the 12 hallmarks of aging."

PRICE
$79–$99/mo
SCORE
8.5 / 10
View at NOVOS
Tru Niagen 300mg NAD+ precursor capsule bottle
Tru Niagen

Tru Niagen (300mg NIAGEN)

The NAD+ precursor that came with the patent and the published trials — ChromaDex's NIAGEN is the most-studied NR on the market, sold direct as Tru Niagen.

PRICE
$50–$90/mo
SCORE
8.6 / 10
View at Tru Niagen
The verdict

These are close picks. Both score in the same range. The right call depends on buyer profile — read the per-buyer recommendations below.

Who should buy which

Pick the NOVOS NOVOS Core if

Longevity-pro and founder buyers who want one daily packet covering twelve aging-research-adjacent compounds, value the scientific advisory board credibility, and prefer convenience over single-ingredient optimization.

Skip if

You have specific lab-identified deficiencies needing higher single-ingredient dosing, you're budget-sensitive at $89/mo, or you prefer dose-flexible single-ingredient stacking.

Pick the Tru Niagen Tru Niagen (300mg NIAGEN) if

Evidence-first buyers who prioritize the most-studied NAD+ precursor with FDA NDI / GRAS status, and longevity-pro buyers who want institutional brand credibility.

Skip if

You specifically want NMN (different precursor pathway), you're tracking aggressive Sinclair-style protocols, or you find the conservative messaging insufficient.

Go deeper

FULL REVIEW
Read the NOVOS NOVOS Core review →
FULL REVIEW
Read the Tru Niagen Tru Niagen (300mg NIAGEN) review →