SUPPLEMENTS · 81 ITEMS

Foundational supplements with real science

Momentous, AG1, Thorne, LMNT, Timeline. 58 longevity supplements reviewed, NSF certification checked per SKU, every price verified against the brand store.

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DEEP REVIEW

Timeline·Supplements

Mitopure

The supplement that single-handedly created the Urolithin A category - a pomegranate metabolite most people can't produce on their own, delivered in a research-backed 500mg dose at $100/month.

Tru Niagen·Supplements

Tru Niagen (300mg NIAGEN)

The NAD+ precursor that came with the patent and the published trials - ChromaDex's NIAGEN is the most-studied NR on the market, sold direct as Tru Niagen.

NOVOS Core

The longevity stack with a Harvard / MIT scientific board behind it - twelve ingredients in one daily packet, designed to address what the team calls "the 12 hallmarks of aging."

Wonderfeel·Supplements

Youngr NMN

900mg of NMN per daily serving - 2-3x what most NMN brands deliver - plus a co-factor stack (trans-resveratrol, ergothioneine, olive-fruit hydroxytyrosol, vitamin D3) the prestige tier doesn't bundle. Formulated by a Harvard MD, Dr. Andrew Salzman. Not the cheapest NMN, but the densest.

BiOptimizers·Supplements

Magnesium Breakthrough

The magnesium that turned the category from "buy whatever's on the shelf" into "wait, which form?" - seven types in one capsule, from the brand that built its name on the question.

Cymbiotika·Supplements

Liposomal Glutathione

The liposomal glutathione that takes encapsulation seriously - phosphatidylcholine carrier, no preservatives, single-serve packets, and a price that lands closer to legacy mid-tier brands than to Quicksilver Scientific.

Approved Science·Supplements

Clinically-Backed Supplements

Condition-specific clinical formulations (Joint, Brain, Immune, Sleep, Gut, Vision - 20+ targeted products) at 50% the price-per-serving of Thorne or Pure Encapsulations. Vegan, third-party tested, manufactured in US cGMP facilities, money-back guarantee. Same clinical-grade quality the prestige brands charge $50-80 per bottle for.

MicroVitamin·Supplements

MicroVitamin

A $65.00 bottle holds 150 capsules and 30 servings, which means the daily dose here is five capsules, not one.

Adagio Teas·Supplements

Matcha Set (SKU 012104)

The Adagio Matcha Set is $64, and the 2-ounce tin inside sells alone for $34, so you are paying $30 for the bowl and the whisk. Bought separately those run $38, which makes the set an $8 saving plus a gift box, not a deep bundle discount. What you are really buying is Adagio's first-harvest Uji matcha and everything needed to whisk it, minus a scoop.

Organised·Supplements

Daily Blend

One scoop standing in for the organ capsules, the collagen tub, and the colostrum jar: a young UK family brand freeze-drying all three into something that reads like food, because it is.

Menopause Relief AM + PM

Menopause supplements are where proprietary blends go to hide. This one prints every single dose on both capsules, and that label transparency is the entire reason it earns a card.

FoodVille·Supplements

MF06 Rechargeable Milk Frother

Four months, two to four drinks a day, and one charge that lasted over a month: the $18 gadget that quietly became the most used piece of gear in our supplement routine.

Cowboy Colostrum·Supplements

Unflavored Colostrum

Most colostrum brands sell you a standardized extract and an IgG number. Cowboy sells the whole thing and no number, and that trade is the entire buying decision.

BUBS Naturals·Supplements

Collagen Peptides

A 20-gram collagen scoop that carries the certification most collagen jars skip: BUBS is in the NSF Certified for Sport database, which means every batch is independently tested.

Prebiotic + Probiotic

Most probiotic labels hide behind a proprietary blend and a big CFU number. This one names all seven strains, doses each, and posts a certificate of analysis for your specific batch.

Clear Wellness 360·Supplements

Magnesium Glycinate Complex

Most one-a-day magnesium capsules make you choose between the well-tolerated bisglycinate form and a price under thirty dollars. This one refuses the choice, and folds in D3 and K2 while it is at it.

Auri Nutrition·Supplements

Super Mushroom Daily Gummies

The front of the bag says 3,000mg of functional mushrooms. The back label says 300mg. Both numbers are true, and the gap between them is the whole story of buying mushroom supplements in 2026.

Health Stix·Supplements

Energy - Berry Bliss Stick Packs

The electrolytes are dosed; the adaptogens hide in a 2400 mg blend. Health Stix Energy is a $23.99 entry into adaptogen hydration stick packs and the flagship of the brand's six-flavor functional line.

More Labs·Supplements

Liquid Focus

Caffeine at 150mg with L-theanine, the one nootropic pairing with a decent evidence base, in a shot that prints the caffeine number.

Men's 18+ Multivitamin

KAL has been formulating supplements since 1932, and its Men’s 18+ multivitamin is the house’s modern flagship: a full-spectrum daily at a price where the buy one get one code effectively doubles the order.

Women's 18+ Multivitamin

KAL’s Women’s 18+ goes beyond the standard multivitamin panel: alongside the B vitamin and antioxidant base it adds L-theanine, chasteberry and inositol, which few daily multis at $36.99 carry.

More Labs·Supplements

Dream Well

A ready-to-drink sleep shot that publishes its melatonin dose: 5mg, which is a real dose and on the higher side of what sleep research tends to favour.

Glorious Daily·Supplements

HeartGlow Chocolate Indulgence 5 in 1 Protein Shake

One 60g scoop-pair carries 22g of organic pea protein, 7g of fiber, 750mg of oat beta-glucan, 200mg of cocoa flavanols, 1000mg of plant omegas, and 100mg of CoQ10, and the 900g bag costs $99.95, verified August 2026. The interesting part is not the formula, it is the published certificate of analysis.

Nitric Oxide Lozenges

One lozenge carries 164 mg of vitamin C and a 220 mg blend of magnesium ascorbate and sodium nitrite, and the 60-count bottle costs $59.98, verified August 2026. The bottle's real differentiator is its founder: Dr. Nathan S. Bryan, a published researcher in nitric oxide biochemistry.

Terra & Co.·Supplements

Brilliant Black Whitening Toothpaste

A $16 charcoal toothpaste that publishes its abrasion data

Marek Supplements·Supplements

Thyroid Support

The supplement arm of Marek Health puts its case on the label: Thyroid Support is a one-a-day, 90-day bottle with all 13 ingredient doses disclosed and the current batch's third-party lab results linked from the product page.

1st Phorm·Supplements

Micronized Creatine Monohydrate

A single-ingredient creatine monohydrate that carries the NSF Certified for Sport mark on its current label, a listing we confirmed in NSF's public certified-products database. The 100-serving tub works out to about 40 cents a serving.

Som Sleep·Supplements

Sleep Powder Drink Mix

A zero-sugar bedtime drink mix that packs magnesium, L-theanine, GABA, B6 and 3 mg melatonin into a $2-per-serving stick.

Wintergreen Dental Gel Toothpaste

A $34.99 toothpaste that swaps abrasives for a chelating agent and asks you to judge it in 4 weeks.

Transparent Labs·Supplements

100% Grass-Fed Whey Protein Isolate

The whey isolate that publishes its lab work instead of asking for trust.

Omne Diem·Supplements

Histamine Digest 30,000 HDU

The highest-potency DAO enzyme in the direct-to-consumer aisle.

True Grace·Supplements

ElectroMag

A zero-sugar electrolyte stick that prints all four mineral amounts on the label: 750 mg sodium, 1,390 mg chloride, 250 mg potassium, and 100 mg magnesium, plus 100 mg of organic cordyceps fruiting body extract. $26.95 for 16 servings or $46.95 for 30, verified August 2026.

Joy Organics·Supplements

THC-Free CBD Sleep Softgels with CBN

Thirty softgels per bottle, each combining broad spectrum CBD, CBN and 3 mg of melatonin in one capsule. $64.95 for the 25 mg strength, $79.95 for the 50 mg, both verified August 2, 2026. We have not tested this product.

Daily Plant Nutrients

NVNQA Daily Plant Nutrients is the plainest thing on the greens shelf: ten dried fruit and vegetable powders in a capsule, with no vitamin layer bolted on, no flavoring, and no shaker bottle, at $35.99 for a bottle of 60.

Grama Wellness·Supplements

Zzzzz

Zzzzz is a $29.95 herbal sleep glycerite dosed by the dropper: seven organic and wild-harvested herbs in a glycerin and water base, with no alcohol in the ingredient list and, as of our August 2, 2026 check, no milligram amount published for any of them.

SuperAkki·Supplements

Next-Gen Akkermansia (Akk11 + Bioferrin)

SuperAkki and Pendulum sell the same organism in opposite forms. Pendulum sells live Akkermansia muciniphila; SuperAkki sells it pasteurized, as a postbiotic, which is why this one is shelf-stable and that one is not.

Liposomal NAD+

Solaray is one of the older names in US supplements (founded 1973), and its Liposomal NAD+ brings the marquee longevity molecule into a value-priced liposomal cap at $42.50, well under the boutique NAD+ brands.

Collagen PRO

Nume's Collagen PRO is a grass-fed, hydrolyzed Type I and III collagen powder at $79.95, the anchor of a broad daily-wellness supplement line.

Sleep Gummies (PeptiSleep)

Brik Sleep Gummies take a genuinely different route to melatonin-free sleep support: 250 mg of PeptiSleep, a plant-derived peptide complex licensed from AI-biotech ingredient company Nuritas, in one nightly gummy at $49.99 for a 30-night pouch, verified July 2026.

Mind Lab Pro·Supplements

v4.0 Universal Nootropic

Mind Lab Pro v4.0 is the fully disclosed nootropic: 11 ingredients, every dose on the label, zero caffeine. At $62.10 to $69 a month, verified July 2026, it charges premium money for that transparency.

Performance Lab·Supplements

NutriGenesis Multi for Men

Performance Lab's NutriGenesis Multi for Men is the cultured-nutrient alternative to the drugstore multivitamin: 24 essential vitamins and minerals grown in live cultures, delivered in vegan pullulan capsules, at $49 for a 30-day supply, verified July 2026.

Sprout Living·Supplements

Epic Protein

Epic Protein puts 20g of organic plant protein in a 38g scoop with no gums, fillers, or flavoring agents, and the 1lb Vanilla Lucuma bag costs $34.95, verified July 2026. The ingredient list is the pitch.

Hydration + Energy Drink Mix

One stick, three jobs: electrolytes, 100 mg of organic caffeine, and a focus stack. At $58 for 30 servings, verified July 2026, Vibras prices itself against your hydration mix and your pre-workout at the same time.

Liquid I.V.·Supplements

Hydration Multiplier

Liquid I.V. Hydration Multiplier is the electrolyte stick pack you have seen everywhere: one packet in 16 ounces of water delivers 500mg of sodium and 370mg of potassium. At $24.99 for a 16-pack, it is the entry-level, mass-market option in the hydration category.

Akkermansia

Pendulum Akkermansia is a single-strain probiotic built around Akkermansia muciniphila, a gut bacterium tied to the mucus lining of the intestine. Pendulum states it is the only live Akkermansia muciniphila probiotic clinically studied to fortify the gut lining, a positioning claim we report as brand-stated.

:rise Cacao Starter Kit

MUD\WTR is the coffee alternative that actually caught on: a USDA-organic blend of cacao, masala chai spices, and adaptogenic mushrooms with roughly one-seventh the caffeine of a cup of coffee, aimed at people who want a morning ritual without the jitters-and-crash cycle.

Terra Mare·Supplements

Morning Restore

Terra Mare is the women's-health supplement line founded by actress Marisa Tomei, and Morning Restore is its flagship: a one-scoop daily powder that stacks marine collagen, seven probiotic strains, six organic mushrooms, and a greens blend aimed at women's healthy aging.

1MD Nutrition·Supplements

Complete Probiotics Platinum

1MD's Complete Probiotics Platinum packs 51 billion CFU across 11 strains plus Nutraflora prebiotic fiber into a single daily capsule. At $49 for a 30-day bottle it sits mid-market, and 1MD frames it as a 12-week microbiota-restoration course rather than a quick fix.

NMN Capsules 500mg

NMN capsules delivering 500mg of the NAD+ precursor per serving, third-party lab tested batch by batch.

Smart Fuel·Supplements

Motivation: Encapsulated

A focus-and-drive capsule as Smart Fuel debut product, for readers who want a nootropic-style pick from an emerging brand.

Complete Optimization for Men

A pre-dosed daily supplement system built for men who want their whole optimization stack in one pack.

Secret Element·Supplements

Citrus Bergamot

A standardized citrus bergamot polyphenol supplement, third-party tested and made in a cGMP USA facility.

Nouro

A daily brain-health capsule stack formulated with Alpha GPC, paraxanthine, taurine and other studied compounds.

1st Phorm·Supplements

Opti-Greens 50 (Natural Berry)

The greens powder people actually finish, because it was engineered for gut comfort and flavor first.

WishGarden Herbs·Supplements

Kick-Ass Immune, Activator

WishGarden has been hand-crafting liquid herbal extracts in Colorado since 1979, and Kick-Ass Immune is the bottle that put the brand on the map. It is a no-frills dropper tincture, not a capsule or gummy.

Troomy Nootropics·Supplements

Focus Lion's Mane Gummies

Lion's Mane is the most popular functional mushroom in the nootropic world, and a gummy is the format most likely to actually get taken daily. Troomy Focus delivers 800mg per serving in a pectin gummy, and it is the brand's most-reviewed product.

Creatine Monohydrate Gummies

Creatine monohydrate is one of the best-studied supplements there is. The catch is daily adherence to a powder. Arq8 puts 5g into four sugar-free gummies, trading a price premium for a format you will actually keep taking.

Creatine

Creatine monohydrate is the rare supplement where the evidence is not in question. The only real question is whether the powder in the tub is clean, and that is where Thorne earns its place.

Magnesium Bisglycinate

Magnesium is one of the few supplements with a genuine population-level case, but the form is everything. Thorne uses the chelated bisglycinate form most people actually tolerate.

Vitamin D + K2 Liquid

Vitamin D and K2 are often taken together for a simple reason, and Thorne packs both into a liquid that sidesteps the main annoyance of D supplements: swallowing yet another softgel.

FullDissolve Nano-Creatine Monohydrate

Creatine monohydrate works; the classic complaint is the grit at the bottom of the glass. Arq8 mills it to a nano particle so it actually dissolves.

BioProtein Technology·Supplements

BioPro+ Growth Factor Sublingual

BioPro+ is a sublingual liquid built on velvet-antler growth-factor extract, marketed as a drug-free, non-synthetic alternative to prescription growth-hormone peptides. It is one of the most-hyped supplements in the longevity-optimizer world, and one of the most-debated.

The Aeternum Company·Supplements

Longevity Molecule Range (NMN, Urolithin A, Fisetin, GlyNAC, TND1128)

The rare longevity supplement brand that carries the entire next-gen molecule shelf - Urolithin A, Fisetin, GlyNAC, NMN, TND1128 - à la carte, instead of charging single-molecule-brand prices for one of them.

Exoceuticals·Supplements

EXO PLUS Anti-Aging Cream

The cellular-signaling biotech that turned exosomes from clinical-research curiosity into a daily anti-aging cream, and the rare longevity-skincare product where the mechanism is actually published, not just brand copy.

CorneaCare·Supplements

Rise Eyelid Wipes + Eye Vitamins

The intervention 16 million Americans need and no one in the longevity stack talks about: clinical eyelid hygiene.

Full Spectrum CBD Gummies 3600mg (120mg/gummy)

The CBD brand that earns the longevity-stack slot the Amazon-influencer gummies don't.

Neurogan Health·Supplements

NMN Capsules 500MG

The "Clinically Dosed, Not Dusted" longevity brand, peer-reviewed dose matching across the whole longevity-supplement stack.

NAD+ Glow Up Set

The first brand to merchandise NAD+ as a skin-longevity vertical, and the one Dr. Lamees Hamdan actually formulated.

The ERLY Essentials

Skincare for the people who tried Drunk Elephant and woke up with a rash. Dermatologist-founded for sensitive, reactive, and rosacea-prone skin - hypoallergenic, fragrance-free, mostly under $50 per product. Built for the buyers prestige brands quietly aggravate.

InVite Health·Supplements

Vitamin D3 3000 IU (90-day supply)

A pharmacist-formulated Vitamin D3 from a US-manufactured supplement retailer with 30+ years of clinical credibility - and the most foundational longevity supplement in any stack at under $25 for a 90-day supply.

EcoWise Wellness·Supplements

Creatine HCl Gummies

Two independent laboratories tested creatine gummies. This one came back at zero.

Genuine Purity·Supplements

Liposomal NMN

NMN wrapped in phospholipid bubbles built to survive your gastric acid - the delivery bet behind a 250mg label where standard NMN powders carry 500-1500mg, though how much of that gap the format actually closes in humans is unsettled. Doctor-formulated, third-party tested, 60 capsules a bottle at one a day, 97-day money-back guarantee.

Renue by Science·Supplements

Liposomal NMN + NAD+ Patches

A premium NMN brand competing on delivery format rather than dose - liposomal, sublingual, and patch options engineered to bypass first-pass metabolism.

Renue Blue·Supplements

Nanoliposome Skin Longevity Stack

Renue by Science's sister brand - same nanoliposome delivery science the parent company applies to internal NMN, now applied to topical skin longevity.

Goodness Lover·Supplements

Gut Health Platform

A nutritionist + advocate-founded gut-health platform that pairs targeted formulations with structured protocols - the right pick when "the gut is the foundation" is more than a slogan.

nutriEffect·Supplements

Performance & Longevity Supplements

An Italian premium-supplement brand bringing EU clean-formulation standards to the energy + focus + longevity stack - alternative to the US-dominated supplement-affiliate market.

NanoNerds·Supplements

Nordic Magnesium Stack

A Scandinavian-design magnesium brand bringing Nordic clean-formulation aesthetics to the supplement category.

Momentous·Supplements

Creatine Monohydrate

The boring supplement with the largest body of research, in a tub whose ingredient panel stops at one line.

AG1 Foundational Nutrition

The greens powder that became a category - premium-priced and worth understanding before buying.

Basic Nutrients 2/Day

The multivitamin clinicians actually recommend - Mayo Clinic partner, methylated B vitamins, no junk.

Recharge Electrolyte Mix

The electrolyte mix that became standard for low-carb, fasted training, and post-sauna rehydration.

Buyer guides

How to choose in this category, with verified prices and honest trade-offs.

Best Creatine

Monohydrate powders and gummies, by third-party testing and cost per serving.

from $29.99

Best NMN Supplements

Wonderfeel vs Renue vs Genuine Purity, plus NR alternatives.

Best Gut Health Supplements

Microbiome picks, probiotic vs prebiotic.

Best Thorne Supplements

The practitioner-grade lineup, ranked.

Is Thorne Worth It?

NSF Certified for Sport and third-party testing, explained.

Best Multivitamin Under $50

Practitioner-grade daily coverage on a budget.

BioPro+ PM Review

The nighttime formula for sleep and recovery.

BioPro+ vs TRT & Peptides

An honest comparison of the options.

Natural Alternative to TRT & HGH

Needle-free options, honestly assessed.

Perimenopause Support

What actually helps, and where a supplement fits.

Hormone Support for Shift Workers

The honest playbook for 12-hour rotations.

Frequently asked

Supplements buyer FAQ

What supplements should I actually take for longevity?

The high-evidence foundational stack: creatine monohydrate (most-studied performance + cognitive supplement), vitamin D + K2 (especially in low-sun latitudes), magnesium (any of the 7 forms BiOptimizers covers), omega-3, and a clinician-vetted multivitamin like Thorne Basic Nutrients 2/Day. Beyond foundational, evidence drops sharply - NMN, urolithin A, and niacin precursors have promising-but-incomplete human data. Always run labs first and supplement based on actual deficiencies, not protocol-stack mimicry.

AG1 vs Thorne - is it worth the premium?

AG1 ($79-99/mo subscription) is a comprehensive greens powder with 75+ ingredients. Thorne Basic Nutrients 2/Day ($35) is a focused multivitamin covering the same essential vitamin/mineral panel as AG1. Thorne is NSF Certified for Sport (banned-substance tested); AG1 isn't. For pure cost-effectiveness on the multi/mineral component, Thorne wins by a wide margin. For the convenience + adaptogen + greens layer, AG1's premium has a real consumer audience. Most clinicians we know prefer Thorne or Momentous for the foundational tier.

Are NAD+ precursors (NMN, NR) actually worth taking?

NMN and NR (Tru Niagen) are the most-marketed longevity supplements after the David Sinclair work, but the human clinical evidence is genuinely incomplete. Cell-line and animal data show NAD+ levels increase with supplementation; clinical outcomes (lifespan, healthspan markers) in humans are still being studied. The honest framing: NMN and NR are reasonable bets on emerging science, not proven longevity interventions. If budget allows, they fit in a longevity stack; if budget is tight, the foundational stack (creatine, vit D, omega-3, magnesium) has stronger evidence per dollar.

Should I bother with the Bryan Johnson Blueprint stack?

Blueprint ($354/mo) is the most comprehensive longevity supplement bundle on the market - 12+ products, 100+ ingredients, designed by Bryan Johnson's team and tracked across his own biomarkers. The case for: it's the most-tested single stack in the category by a single user. The case against: Bryan Johnson is one person, and what works for his physiology may not transfer to yours. For buyers wanting a turnkey premium stack and the brand-experience component, Blueprint delivers. For evidence-per-dollar, the foundational stack from Thorne + Momentous + LMNT covers 80% of the practical benefit at 25% of the cost.

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