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Independent·Affiliate-disclosed·Spec-verified·Prices tracked daily
DIAGNOSTICS · 27 ITEMS

Diagnostics for the longevity-curious

Prenuvo whole-body MRI, InsideTracker, Galleri multi-cancer screen. The diagnostic layer of a serious longevity practice.

TIER
FOR
Marek Health comprehensive hormone optimization dashboard
DEEP REVIEW
Marek Health·Diagnostics

Guided Optimization (pay-per-service)

The premium guided-protocol HRT platform where the YouTube longevity crowd actually gets their bloodwork done - broader, deeper, and more clinically aggressive than Hone.

PRICE
$250 to $2,000/test
SCORE
8.9 / 10
TruDiagnostic TruAge Complete epigenetic age test kit
DEEP REVIEW
TruDiagnostic·Diagnostics

TruAge COMPLETE Epigenetic Test

The biological-age epigenetic test the longevity crowd actually uses - and the only consumer-accessible kit running multiple validated clocks (DunedinPACE, Horvath, OMICmAge) in one panel.

PRICE
$499 to $849/test
SCORE
8.6 / 10
Labcorp OnDemand at-home and in-person lab testing
DEEP REVIEW
Labcorp OnDemand·Diagnostics

OnDemand Lab Testing

Most direct-to-consumer blood tests are startups that send your sample to a third-party lab. Labcorp OnDemand skips the middle layer: it is the consumer storefront of Labcorp itself, one of the two national reference labs that already run a large share of US clinical bloodwork.

PRICE
$49 to $651/test
SCORE
8.5 / 10
Hone Health at-home hormone test kit and telehealth dashboard
DEEP REVIEW
Hone Health·Diagnostics

Men's Health + TRT Membership

The men's telehealth platform that pulled TRT out of the urology clinic and into the iPhone - and the one most buyers compare everything else against.

PRICE
$65 to $155/mo
SCORE
8.4 / 10
Mito Health brand banner
DEEP REVIEW
Mito Health·Diagnostics

Mito Health Membership

A comprehensive-diagnostics platform where members can upload past bloodwork from other providers so every result reads together and trends over time: 117 to 178 biomarkers depending on panel, biological age and AI action plans, sold as one-time purchases from $89.61 for members alongside an optional $9/mo membership, with no annual commitment.

PRICE
$89.61 to $278.3
SCORE
8.3 / 10
Maximus Health telehealth platform for testosterone and metabolic protocols
DEEP REVIEW
Maximus Health·Diagnostics

Performance Protocol Membership

The performance-positioning telehealth play - TRT, enclomiphene, and semaglutide bundled for buyers who explicitly want "optimization" branding rather than "men's health" branding.

PRICE
$99.99 to $249.99/mo
SCORE
8.3 / 10
CircleDNA Premium at-home DNA test kit and app
DEEP REVIEW
CircleDNA·Diagnostics

Premium DNA Test

Most consumer DNA tests give you ancestry plus a handful of trait cards. CircleDNA's Premium test goes the other direction: one cheek swab, sequenced on Illumina NGS hardware, returned as 500+ reports across diet, fitness, sleep, drug response, disease risk, and family planning.

PRICE
$349 to $629/test
SCORE
7.9 / 10
YorkTest Premium Food Sensitivity Test kit box with finger-prick collection materials
YorkTest·Diagnostics

Premium Food Sensitivity Test

YorkTest's Premium Food Sensitivity Test mails a finger-prick sample to the brand's own 40-year-old laboratory and returns a color-coded IgG reactivity score for 200 foods and drinks within 7 days. Read it as a structured starting map for an elimination diet, not a diagnosis.

PRICE
$139 to $199
TIER
mid
Black airless pump bottle of Happy Head Topical Rx SuperSolution, labeled Dermatologist-Designed and Net 1oz (30mL), standing on a white stone block with its black cap beside it against an off-white background
Happy Head·Diagnostics

Topical SuperSolution (finasteride 0.3% + minoxidil 8%)

An online dermatologist consult that ends in a custom-compounded prescription: Happy Head's Topical SuperSolution combines finasteride 0.3% and minoxidil 8% in a once-a-day liposomal base for $79 a month on subscription.

PRICE
$79 to $99
TIER
entry
Oova Fertility Hormone Kit boxes with wrapped LH, PdG, and E3G urine test strips and test cassettes
Oova·Diagnostics

Fertility Hormone Kit (OCK01)

Oova turns a urine strip and a phone camera into numeric LH, E3G, and PdG readings, replacing the binary smiley-face ovulation test with an actual hormone curve.

PRICE
$129 to $159
TIER
mid
Tablet showing the FitnessGenes reports dashboard with Biological Ageing, Heart Health, Blood Sugar, Sleep and Vitamins traits
FitnessGenes·Diagnostics

DNA Data Upload

If you already spat in a tube for 23andMe, this is the $199 way to get FitnessGenes' full report set without buying a second kit.

PRICE
$199
TIER
mid
FitnessGenes DNA Collection Kit box held in two hands
FitnessGenes·Diagnostics

DNA Saliva Test

A $399 all-in saliva kit from a UK genetics company whose two founders both hold PhDs, with the sample read in an ISO 17025-accredited lab.

PRICE
$399
TIER
premium
Sesame Plus membership hero image showing a patient using Sesame's cash-pay healthcare marketplace
Sesame·Diagnostics

Sesame Plus

A $99-a-year membership that discounts cash-pay doctor visits and includes one free blood lab, no insurance required.

PRICE
$10.99 to $99
TIER
entry
Walk-In Lab blood and urine test panel
Walk-In Lab·Diagnostics

Wellness #3 Extreme Blood and Urine Test Panel

8 blood and urine test groups, including CMP-14, CBC, lipids, thyroid with TSH, and a complete urinalysis, for $299 with no doctor visit.

PRICE
$299
TIER
mid
Walk-In Lab blood test panel
Walk-In Lab·Diagnostics

Wellness #2 Essential Blood Test Panel

Six test groups covering metabolic, lipid, thyroid, and blood count markers in one $175 draw, ordered online without a doctor visit.

PRICE
$175
TIER
entry
Superpower annual blood-panel membership dashboard
Superpower·Diagnostics

Annual Membership

One annual membership at $349 covering 150+ biomarkers across a baseline draw and a retest, with biological age tracking and a care team included rather than sold separately.

PRICE
$349/yr
TIER
mid
Everlywell at-home Thyroid Test collection kit
Everlywell·Diagnostics

Thyroid Test

The Everlywell Thyroid Test is an at-home finger-prick panel that measures the four markers most people actually want when they suspect a thyroid issue: TSH, Free T3, Free T4, and TPO antibodies. It is $149, physician-reviewed, and processed in CLIA-certified labs.

PRICE
$149
TIER
mid
RunStar 8E body fat smart scale
RunStar·Diagnostics

8E Body Fat Scale

Body-composition scales are the cheapest way to track a trend that matters more than raw weight: how much of you is muscle versus fat, and whether it is moving the right direction. The RunStar 8E is the value pick, an 8-electrode scale that reads about 28 metrics for around $100.

PRICE
$100
TIER
entry
myLAB Box Total Box 14-panel at-home STD test kit
myLAB Box·Diagnostics

Total Box (14-Panel)

myLAB Box's Total Box is its flagship 14-panel at-home STD test: one discreet, self-collected kit that screens for the widest range of common infections, with CLIA-certified lab results in 3 to 7 business days and a free physician consult if anything comes back positive.

PRICE
$379 to $409
TIER
premium
Personalabs Comprehensive Wellness Profile blood test
Personalabs·Diagnostics

Comprehensive Wellness Profile

A single order that maps your core wellness biomarkers, drawn at 4,000-plus Labcorp and Quest locations nationwide, with the physician order included.

PRICE
$150
TIER
mid
Living DNA Wellbeing Kit at-home DNA test
Living DNA·Diagnostics

Wellbeing Kit

An at-home DNA test reporting genetic markers related to nutrition, vitamins, and exercise so you can personalize your routine.

PRICE
$89
TIER
entry
SiPhox Health at-home blood testing kit
SiPhox Health·Diagnostics

At-Home Biomarker Test

The at-home blood panel that skips the lab visit and the needle: a small upper-arm sample, up to 60 biomarkers, results in 7-10 days with an AI-built action plan. The lowest-friction way to actually test as often as longevity tracking wants you to.

PRICE
$124
TIER
entry
Hume Health Body Pod - at-home bioelectrical impedance body composition scanner
Hume Health·Diagnostics

Body Pod

The body-composition tracker that closes the catalog's biggest measurement gap: knowing whether your weight change is muscle or fat, without booking a DEXA scan.

PRICE
$229
TIER
entry
HealthLabs.com direct-to-consumer lab testing
HealthLabs.com·Diagnostics

Direct-to-Consumer Lab Testing

The shortcut for buyers who need a specific lab test without booking a doctor visit, waiting for the order, and battling insurance.

PRICE
$59 to $459
TIER
mid
Prenuvo whole-body MRI scanner
Prenuvo·Diagnostics

Whole-Body MRI

The full-body MRI scan that became the longevity cocktail-party flex - and the diagnostic everyone debates.

PRICE
$1,199 to $4,999/test
TIER
ultra premium
InsideTracker biomarker dashboard
InsideTracker·Diagnostics

Ultimate Plan

The OG of "blood test + AI advice" - InsideTracker was doing this 10 years before Function Health existed.

PRICE
$199 to $647/test
TIER
mid
Galleri multi-cancer early detection blood test
Galleri·Diagnostics

Multi-Cancer Early Detection Test

A blood test screening for 50+ cancers - the most-debated longevity diagnostic of 2026.

PRICE
$949/test
TIER
premium
Frequently asked

Diagnostics buyer FAQ

What is the best longevity diagnostic in 2026?

Depends on what you're trying to learn. For comprehensive biomarker tracking with AI insights, Function Health ($365/yr for 160+ biomarkers 2x/year) is the editor's pick. For clinician-led hormone optimization, Marek Health is the gold standard. For full-body cancer screening, Prenuvo whole-body MRI ($999-2,499). For epigenetic age, TruDiagnostic TruAge. For multi-cancer early detection blood test, Galleri.

Function Health vs InsideTracker?

Function Health ($365/yr) tests 160+ biomarkers 2x/year with AI insights and clinician review - the comprehensive longevity-medicine play. InsideTracker ($300+ per panel, no subscription required) tests fewer markers with optimized recommendation engine - better for spot baselines and trying out lab tracking before committing. For serious longevity buyers, Function Health is the deeper investment; for first-time lab buyers, InsideTracker is the lower-friction starting point.

Is whole-body MRI worth the cost?

Prenuvo whole-body MRI ($999-2,499) is the most controversial diagnostic in the longevity space. The case for: catches incidental findings traditional preventive care misses (small tumors, aneurysms, structural abnormalities). The case against: high false-positive rate, the worry generated often outweighs the actual clinical utility, and no major medical society currently endorses it as routine screening. For buyers with personal or family cancer history, the math may favor it. For everyone else, it's a buyer-preference decision rather than a clear medical-necessity one.

How often should I run lab work?

For longevity-focused tracking, 2x per year is the consensus among longevity practitioners - once at baseline, once at 6 months to assess intervention response. Function Health bundles this cadence at $365/yr. For active hormone optimization protocols (TRT, peptides), every 90 days is standard while titrating, dropping to every 6 months once stable. For one-time baseline curiosity buyers, an annual InsideTracker or single-visit panel is sufficient.

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