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Head-to-head buyer guide

Timeline Mitopure vs Tru Niagen Tru Niagen (300mg NIAGEN)

Specs, prices, editor verdict, and who should buy which — compared side-by-side.

By Ryan · Editor & Founder
Published May 3, 2026
Timeline
Timeline

Mitopure

The supplement that single-handedly created the Urolithin A category — a pomegranate metabolite most people can't produce on their own, delivered in a research-backed 500mg dose at $100/month.

PRICE
$90–$120/mo
SCORE
8.8 / 10
View at Timeline
Tru Niagen 300mg NAD+ precursor capsule bottle
Tru Niagen

Tru Niagen (300mg NIAGEN)

The NAD+ precursor that came with the patent and the published trials — ChromaDex's NIAGEN is the most-studied NR on the market, sold direct as Tru Niagen.

PRICE
$50–$90/mo
SCORE
8.6 / 10
View at Tru Niagen
The verdict

These are close picks. Both score in the same range. The right call depends on buyer profile — read the per-buyer recommendations below.

Side-by-side specs

SpecTimeline MitopureTru Niagen Tru Niagen (300mg NIAGEN)
price$90–$120/mo$50–$90/mo
active ingredientUrolithin A (Mitopure)Nicotinamide Riboside (NIAGEN)
dose500mg/day300mg/day
researchUniversity of Lausanne RCTs~30+ peer-reviewed human trials

Timeline Mitopure also publishes: certifications, forms

Tru Niagen Tru Niagen (300mg NIAGEN) also publishes: regulatoryStatus, distribution

Who should buy which

Pick the Timeline Mitopure if

Longevity-pro buyers who already have foundational supplements (creatine, omega-3, multivitamin) dialed in and want one mitochondrial-research-adjacent addition with peer-reviewed dosing.

Skip if

You're building your first stack (start with creatine + multi + omega-3), you're budget-sensitive at $100/mo, or you want results trackable in weeks rather than months.

Pick the Tru Niagen Tru Niagen (300mg NIAGEN) if

Evidence-first buyers who prioritize the most-studied NAD+ precursor with FDA NDI / GRAS status, and longevity-pro buyers who want institutional brand credibility.

Skip if

You specifically want NMN (different precursor pathway), you're tracking aggressive Sinclair-style protocols, or you find the conservative messaging insufficient.

Go deeper

FULL REVIEW
Read the Timeline Mitopure review →
FULL REVIEW
Read the Tru Niagen Tru Niagen (300mg NIAGEN) review →