Timeline Mitopure vs Tru Niagen (300mg NIAGEN)
Specs, prices, editor verdict, and who should buy which, compared side by side.
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Timeline Mitopure (premium, $89 to $827.92/mo) vs Tru Niagen (300mg NIAGEN) (premium, $49 to $244/mo). Different tools for different jobs (see the per-product details below).
Compared on 3 shared specs · editor scores 8.8 vs 8.6 · same category (supplement).
Our editor scores are within half a point (8.8 and 8.6), so the right pick comes down to fit rather than score. The Tru Niagen (300mg NIAGEN) starts at $49/mo and the Timeline Mitopure at $89/mo. The per-buyer recommendations below say who each one suits.
Side-by-side specs
| Spec | Timeline Mitopure | Tru Niagen (300mg NIAGEN) |
|---|---|---|
| price | $89 to $827.92/mo | $49 to $244/mo |
| active ingredient | Urolithin A (Mitopure) | Nicotinamide Riboside (NIAGEN) |
| dose | 500mg/day | 300mg/day |
| research | University of Lausanne RCTs | ~30+ peer-reviewed human trials |
Timeline Mitopure also publishes: certifications, forms
Tru Niagen (300mg NIAGEN) also publishes: regulatory status, distribution
Who should buy which
Longevity-pro buyers who already have foundational supplements (creatine, omega-3, multivitamin) dialed in and want one mitochondrial-research-adjacent addition with peer-reviewed dosing.
You're building your first stack (start with creatine + multi + omega-3), you're budget-sensitive at $100/mo, or you want results trackable in weeks rather than months.
Evidence-first buyers who prioritize the most-studied NAD+ precursor with FDA NDI / GRAS status, and longevity-pro buyers who want institutional brand credibility.
You specifically want NMN (different precursor pathway), you're tracking aggressive Sinclair-style protocols, or you find the conservative messaging insufficient.
Go deeper
Frequently asked
Which is better, the Timeline Mitopure or the Tru Niagen (300mg NIAGEN)?
Our editor scores are within half a point (8.8 and 8.6), so the right pick comes down to fit rather than score. The Tru Niagen (300mg NIAGEN) starts at $49/mo and the Timeline Mitopure at $89/mo. The per-buyer recommendations below say who each one suits.
How much do they cost?
Timeline Mitopure: $89 to $827.92. Tru Niagen (300mg NIAGEN): $49 to $244. Prices are verified against the manufacturer; check the live links for current pricing.
Who should buy which one?
Timeline Mitopure: Longevity-pro buyers who already have foundational supplements (creatine, omega-3, multivitamin) dialed in and want one mitochondrial-research-adjacent addition with peer-reviewed dosing. Tru Niagen (300mg NIAGEN): Evidence-first buyers who prioritize the most-studied NAD+ precursor with FDA NDI / GRAS status, and longevity-pro buyers who want institutional brand credibility.
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