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Head-to-head buyer guide

Timeline Mitopure vs Tru Niagen (300mg NIAGEN)

Specs, prices, editor verdict, and who should buy which - compared side-by-side.

By Ryan · Founder
Updated Aug 14, 2026

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Quick verdict

Timeline Mitopure (premium, $89 to $827.92/mo) vs Tru Niagen Tru Niagen (300mg NIAGEN) (premium, $49 to $244/mo) - different tools for different jobs (see the per-product details below).

Compared on 3 shared specs · editor scores 8.8 vs 8.6 · same category (supplement).

Timeline Mitopure Urolithin A softgels
Timeline

Mitopure

The supplement that single-handedly created the Urolithin A category - a pomegranate metabolite most people can't produce on their own, delivered in a research-backed 500mg dose at $100/month.

PRICE
$89 to $827.92/mo
SCORE
8.8 / 10
Tru Niagen 300mg NAD+ precursor capsule bottle
Tru Niagen

Tru Niagen (300mg NIAGEN)

The NAD+ precursor that came with the patent and the published trials - ChromaDex's NIAGEN is the most-studied NR on the market, sold direct as Tru Niagen.

PRICE
$49 to $244/mo
SCORE
8.6 / 10
View at Tru Niagen
The verdict

These are close picks. Both score in the same range. The right call depends on buyer profile - read the per-buyer recommendations below.

Side-by-side specs

SpecTimeline MitopureTru Niagen Tru Niagen (300mg NIAGEN)
price$89 to $827.92/mo$49 to $244/mo
active ingredientUrolithin A (Mitopure)Nicotinamide Riboside (NIAGEN)
dose500mg/day300mg/day
researchUniversity of Lausanne RCTs~30+ peer-reviewed human trials

Timeline Mitopure also publishes: certifications, forms

Tru Niagen Tru Niagen (300mg NIAGEN) also publishes: regulatoryStatus, distribution

Who should buy which

Pick the Timeline Mitopure if

Longevity-pro buyers who already have foundational supplements (creatine, omega-3, multivitamin) dialed in and want one mitochondrial-research-adjacent addition with peer-reviewed dosing.

Skip if

You're building your first stack (start with creatine + multi + omega-3), you're budget-sensitive at $100/mo, or you want results trackable in weeks rather than months.

Pick the Tru Niagen Tru Niagen (300mg NIAGEN) if

Evidence-first buyers who prioritize the most-studied NAD+ precursor with FDA NDI / GRAS status, and longevity-pro buyers who want institutional brand credibility.

Skip if

You specifically want NMN (different precursor pathway), you're tracking aggressive Sinclair-style protocols, or you find the conservative messaging insufficient.

Go deeper

FULL REVIEW
Read the Timeline Mitopure review →
FULL REVIEW
Read the Tru Niagen Tru Niagen (300mg NIAGEN) review →

Frequently asked

Which is better, the Timeline Mitopure or the Tru Niagen (300mg NIAGEN)?

They are closely matched on our scoring, so the right pick comes down to your priorities. The verdict and spec table above compare them on price, features, and who each one suits.

How much do they cost?

Timeline Mitopure: $89 to $827.92. Tru Niagen (300mg NIAGEN): $49 to $244. Prices are verified against the manufacturer; check the live links for current pricing.

Who should buy which one?

Timeline Mitopure: Longevity-pro buyers who already have foundational supplements (creatine, omega-3, multivitamin) dialed in and want one mitochondrial-research-adjacent addition with peer-reviewed dosing. Tru Niagen (300mg NIAGEN): Evidence-first buyers who prioritize the most-studied NAD+ precursor with FDA NDI / GRAS status, and longevity-pro buyers who want institutional brand credibility.

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