SUPPLEMENTS · 28 ITEMS

Foundational supplements with real science

Momentous, AG1, Thorne, LMNT. NSF-certified daily supplements vetted by clinicians.

TIER

FOR

Mitopure

The supplement that single-handedly created the Urolithin A category - a pomegranate metabolite most people can't produce on their own, delivered in a research-backed 500mg dose at $100/month.

Tru Niagen·Supplements

Tru Niagen (300mg NIAGEN)

The NAD+ precursor that came with the patent and the published trials - ChromaDex's NIAGEN is the most-studied NR on the market, sold direct as Tru Niagen.

NOVOS Core

The longevity stack with a Harvard / MIT scientific board behind it - twelve ingredients in one daily packet, designed to address what the team calls "the 12 hallmarks of aging."

Wonderfeel·Supplements

Youngr NMN

900mg of NMN per daily serving - 2-3x what most NMN brands deliver - plus a co-factor stack (resveratrol, ergothioneine, hyaluronic acid) the prestige tier doesn't bundle. Formulated by ex-Genentech scientists. Not the cheapest NMN, but the densest.

TruLab Peptides·Supplements

Research Peptides Catalog

A research-peptide catalog with the rarest combination in the category - third-party mass-spec verification published per lot, public CoAs, and an actually navigable storefront.

BiOptimizers·Supplements

Magnesium Breakthrough

The magnesium that turned the category from "buy whatever's on the shelf" into "wait, which form?" - seven types in one capsule, from the brand that built its name on the question.

Cymbiotika·Supplements

Liposomal Glutathione

The liposomal glutathione that takes encapsulation seriously - phosphatidylcholine carrier, no preservatives, glass bottle, and a price that lands closer to legacy mid-tier brands than to Quicksilver Scientific.

Approved Science·Supplements

Clinically-Backed Supplements

Condition-specific clinical formulations (Joint, Brain, Immune, Sleep, Gut, Vision - 20+ targeted products) at 50% the price-per-serving of Thorne or Pure Encapsulations. Vegan, third-party tested, manufactured in US cGMP facilities, money-back guarantee. Same clinical-grade quality the prestige brands charge $50-80 per bottle for.

BioProtein Technology·Supplements

BioPro+ Growth Factor Sublingual

BioPro+ is a sublingual liquid built on velvet-antler growth-factor extract, marketed as a drug-free, non-synthetic alternative to prescription growth-hormone peptides. It is one of the most-hyped supplements in the longevity-optimizer world, and one of the most-debated.

The Aeternum Company·Supplements

Longevity Molecule Range (NMN, Urolithin A, Fisetin, GlyNAC, TND1128)

The rare longevity supplement brand that carries the entire next-gen molecule shelf - Urolithin A, Fisetin, GlyNAC, NMN, TND1128 - à la carte, instead of charging single-molecule-brand prices for one of them.

Exoceuticals·Supplements

EXO PLUS Anti-Aging Cream

The cellular-signaling biotech that turned exosomes from clinical-research curiosity into a daily anti-aging cream, and the rare longevity-skincare product where the mechanism is actually published, not just brand copy.

CorneaCare·Supplements

Rise Eyelid Wipes + Eye Vitamins

The intervention 16 million Americans need and no one in the longevity stack talks about: clinical eyelid hygiene.

Full Spectrum CBD Gummies 3600mg (120mg/gummy)

The CBD brand that earns the longevity-stack slot the Amazon-influencer gummies don't.

Neurogan Health·Supplements

NMN Capsules 500MG

The "Clinically Dosed, Not Dusted" longevity brand, peer-reviewed dose matching across the whole longevity-supplement stack.

NAD+ Glow Up Set

The first brand to merchandise NAD+ as a skin-longevity vertical, and the one Dr. Lamees Hamdan actually formulated.

The ERLY Essentials

Skincare for the people who tried Drunk Elephant and woke up with a rash. Dermatologist-founded for sensitive, reactive, and rosacea-prone skin - hypoallergenic, fragrance-free, mostly under $50 per product. Built for the buyers prestige brands quietly aggravate.

InVite Health·Supplements

Vitamin D3 1000 IU (90-day supply)

A pharmacist-formulated Vitamin D3 from a US-manufactured supplement retailer with 30+ years of clinical credibility - and the most foundational longevity supplement in any stack at under $25 for a 90-day supply.

EcoWise Wellness·Supplements

Creatine HCl Gummies

Creatine in gummy form sounds like a marketing gimmick - until you realize compliance is the entire game with creatine, and a daily gummy beats a daily scoop of monohydrate sitting in a drawer.

Genuine Purity·Supplements

Liposomal NMN

NMN wrapped in phospholipid bubbles built to survive your gastric acid - the delivery technology that lets a 250mg liposomal dose match what 500-1500mg of standard NMN powder delivers to your bloodstream. Doctor-formulated, third-party tested, 30-day money-back guarantee.

Renue by Science·Supplements

Liposomal NMN + NAD+ Patches

A premium NMN brand competing on delivery format rather than dose - liposomal, sublingual, and patch options engineered to bypass first-pass metabolism.

Renue Blue·Supplements

Nanoliposome Skin Longevity Stack

Renue by Science's sister brand - same nanoliposome delivery science the parent company applies to internal NMN, now applied to topical skin longevity.

Goodness Lover·Supplements

Gut Health Platform

A nutritionist + advocate-founded gut-health platform that pairs targeted formulations with structured protocols - the right pick when "the gut is the foundation" is more than a slogan.

nutriEffect·Supplements

Performance & Longevity Supplements

An Italian premium-supplement brand bringing EU clean-formulation standards to the energy + focus + longevity stack - alternative to the US-dominated supplement-affiliate market.

NanoNerds·Supplements

Nordic Magnesium Stack

A Scandinavian-design magnesium brand bringing Nordic clean-formulation aesthetics to the supplement category.

Momentous·Supplements

Creatine Monohydrate

The boring supplement with the largest body of research - and the brand most longevity clinicians actually recommend.

AG1 Foundational Nutrition

The greens powder that became a category - premium-priced and worth understanding before buying.

Basic Nutrients 2/Day

The multivitamin clinicians actually recommend - Mayo Clinic partner, methylated B vitamins, no junk.

Recharge Electrolyte Mix

The electrolyte mix that became standard for low-carb, fasted training, and post-sauna rehydration.

Frequently asked

Supplements buyer FAQ

What supplements should I actually take for longevity?

The high-evidence foundational stack: creatine monohydrate (most-studied performance + cognitive supplement), vitamin D + K2 (especially in low-sun latitudes), magnesium (any of the 7 forms BiOptimizers covers), omega-3, and a clinician-vetted multivitamin like Thorne Basic Nutrients 2/Day. Beyond foundational, evidence drops sharply - NMN, urolithin A, and niacin precursors have promising-but-incomplete human data. Always run labs first and supplement based on actual deficiencies, not protocol-stack mimicry.

AG1 vs Thorne - is it worth the premium?

AG1 ($79-99/mo subscription) is a comprehensive greens powder with 75+ ingredients. Thorne Basic Nutrients 2/Day ($35) is a focused multivitamin covering the same essential vitamin/mineral panel as AG1. Thorne is NSF Certified for Sport (banned-substance tested); AG1 isn't. For pure cost-effectiveness on the multi/mineral component, Thorne wins by a wide margin. For the convenience + adaptogen + greens layer, AG1's premium has a real consumer audience. Most clinicians we know prefer Thorne or Momentous for the foundational tier.

Are NAD+ precursors (NMN, NR) actually worth taking?

NMN and NR (Tru Niagen) are the most-marketed longevity supplements after the David Sinclair work, but the human clinical evidence is genuinely incomplete. Cell-line and animal data show NAD+ levels increase with supplementation; clinical outcomes (lifespan, healthspan markers) in humans are still being studied. The honest framing: NMN and NR are reasonable bets on emerging science, not proven longevity interventions. If budget allows, they fit in a longevity stack; if budget is tight, the foundational stack (creatine, vit D, omega-3, magnesium) has stronger evidence per dollar.

Should I bother with the Bryan Johnson Blueprint stack?

Blueprint ($354/mo) is the most comprehensive longevity supplement bundle on the market - 12+ products, 100+ ingredients, designed by Bryan Johnson's team and tracked across his own biomarkers. The case for: it's the most-tested single stack in the category by a single user. The case against: Bryan Johnson is one person, and what works for his physiology may not transfer to yours. For buyers wanting a turnkey premium stack and the brand-experience component, Blueprint delivers. For evidence-per-dollar, the foundational stack from Thorne + Momentous + LMNT covers 80% of the practical benefit at 25% of the cost.

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