NMN for Dogs and Cats: Renue Pet Chews Reviewed (2026)
Renue by Science sells NMN soft chews for dogs and cats at $34.95 for 60. The dog chew carries 77 mg of NMN inside a nine-ingredient joint formula, the cat chew 35 mg and fish oil. Only one of them is cheap per milligram.
Renue by Science now sells NMN soft chews for pets: $34.95 for 60 chews, one jar for dogs and a separately formulated one for cats, both verified in stock on 2026-08-06. Renue publishes the dose for each, on a PRODUCT FACTS panel that lives in the product gallery as an image rather than in the page text. The dog chew carries 77 mg of NMN. The cat chew carries 35 mg. Those two numbers decide this purchase, and they point in opposite directions.
Run the arithmetic and the dog chew is the cheapest NAD precursor on this shelf by a wide margin: $0.58 a chew, about $0.0076 per milligram of NMN, against roughly $0.0167 per milligram for the Zesty Paws Healthy Aging NAD+ Precursor at $59.97 for 60 capsules (verified 2026-08-06). That is about 55 percent less per milligram. The cat chew, at the same $0.58 for 35 mg, comes to $0.0166 per milligram, which is the same price as Zesty Paws. Same brand, same sticker, same format, and only one of them is a bargain.
There is a second thing the dog label tells you, and it matters more than the price. The dog chew is not really an NMN product.
Quick answer
- Dog owner who wants joint-formula ingredients and NMN together: the PET NMN Longevity Chews for Dogs at $34.95 (verified 2026-08-06), because 77 mg of NMN rides along with 250 mg of glucosamine and the NMN still costs less per milligram than the capsule alternative.
- Cat owner shopping a shelf nobody stocks: the PET NMN Longevity Chews for Cats at $34.95 (verified 2026-08-06), because very few brands formulate an NAD precursor for cats at all. Buy it for that, not for the price per milligram.
- Anyone who wants an NAD precursor on its own: the Zesty Paws Healthy Aging NAD+ Precursor at $59.97 (verified 2026-08-06), because 60 mg of Niagen per capsule is the whole formula, with no joint stack attached.
The three-way comparison
Prices below are dated. Confirm the live figure before you buy, and note that the last column is the one that separates these products.
| Product | Price (verified) | Count | Cost per unit | NAD precursor per unit | Cost per mg |
|---|---|---|---|---|---|
| Renue PET NMN for Dogs | $34.95 (2026-08-06) | 60 chews, 5.3 oz | $0.58 per chew | 77 mg NMN | $0.0076 |
| Renue PET NMN for Cats | $34.95 (2026-08-06) | 60 chews, 1.59 oz | $0.58 per chew | 35 mg NMN | $0.0166 |
| Zesty Paws Healthy Aging NAD+ | $59.97 (2026-08-06) | 60 capsules | $1.00 per capsule | 60 mg Niagen | $0.0167 |
One caveat before you lean on that last column. Renue uses NMN, nicotinamide mononucleotide. Zesty Paws uses Niagen, the branded form of nicotinamide riboside. Both are NAD precursors, they are different molecules with different absorption paths, and neither has been shown to do anything for a pet's lifespan. Cost per milligram is a useful sanity check on what you are paying for, not a verdict on which one works better.
The dog chew: a joint formula with NMN in it
Here is the full active list, per 2.5 g chew, straight off the panel: glucosamine HCl 250 mg, flaxseed powder 100 mg, NMN 77 mg, chondroitin sulfate (avian) 50 mg, MSM 50 mg, resveratrol 40 mg, Boswellia serrata extract 35 mg, fish oil 25 mg, vitamin C 10 mg. Nine actives, 637 mg in total. NMN is 12 percent of that. The four ingredients most people associate with joint supplements, glucosamine, chondroitin, MSM and Boswellia, are 385 mg, or about 60 percent.
So if you came here looking for "NMN for my dog," understand what lands on the doorstep. This competes as much with a mobility chew like the Innovet Pet Advanced Mobility Support Chews as it does with a pure NAD precursor. That is good news if your senior dog was getting a joint supplement anyway, because you are buying both in one chew and the NMN is cheaper per milligram than buying it separately. It is bad news if your dog is already on glucosamine, because you will be doubling the dose without meaning to. Take both labels to your vet instead of stacking them yourself.
Dosing scales by weight: 1 chew daily up to 40 lb, 2 chews from 41 to 80 lb, 3 chews above 80 lb, which is 77, 154, or 231 mg of NMN a day. At $0.58 a chew that is about $17 a month for a 30 lb terrier, $35 a month for a 60 lb retriever, and about $52 a month for a 90 lb shepherd, where a jar of 60 empties in 20 days. The soft chew is the honest advantage over a capsule: no pill pocket, no cheese, no negotiation. The label also states the product contains shellfish and fish, which is a hard stop for dogs that react to either.
Two claims from Renue that we can attribute but not verify: the brand says it teamed up with experts in the longevity field and top veterinarians, without naming a panel, and says it has heard from hundreds of customers who believe their pets are benefiting. Customer belief is not evidence. Renue's own page carries the FDA disclaimer that the product is not intended to diagnose, treat, cure or prevent any disease.
The cat chew: the rarer product, at an ordinary price
The cat aisle is close to empty. Most pet longevity supplements are dog products that mention cats in passing, and Renue built a separate cat formula instead. The label supports that: two actives, NMN 35 mg and fish oil 25 mg, against the dog chew's nine. It is a genuinely different product, differentiated by what is in it rather than by how big the chew is.
Where it gives ground is the price per milligram, and this is the part worth being blunt about. At $0.0166 per milligram of NMN, the cat chew costs the same as Zesty Paws costs per milligram of Niagen. The dog chew is 55 percent cheaper per milligram. The cat version is worth buying because the shelf is nearly bare and because it is formulated for the animal, not because the economics are good.
Dosing is 1 chew daily up to 10 lb and 2 chews above 10 lb, so a 9 lb cat is about $0.58 a day and a jar lasts two months, while an 11 lb cat is $1.17 a day and goes through a jar a month. Two pounds of cat separates roughly $17 a month from roughly $35. The label states the product contains fish. Add the ordinary risk that your cat simply declines a soft chew, and the fact that cat-specific evidence on NAD precursors is thinner than dog evidence, which is already early. The vet conversation is not a formality here.
One loose end we could not tie off: Renue's cat panel states a 2.5 g chew, the same figure printed on the dog panel, which does not reconcile with a 45 g net weight across 60 chews. We are flagging it rather than picking a number, and we do not publish a per-chew weight for the cat version.
The single-ingredient alternative: Zesty Paws
If you want an NAD precursor and nothing else, the Zesty Paws Healthy Aging NAD+ Precursor is the direct answer for dogs. It is $59.97 for 60 bacon-flavored capsules (verified 2026-08-06), which is $1.00 per capsule and 60 mg of Niagen each. Niagen is the branded nicotinamide riboside used in human longevity products, so you can reason about what you are giving and discuss one number with your vet rather than nine. A 30-sachet powder version of the same formula runs $49.97 for dogs that refuse capsules.
Where it gives ground: price, breadth and species. It is 72 percent more expensive per unit than the Renue chew and roughly 2.2 times the price per milligram, it is a capsule rather than a soft chew, it carries no joint-formula ingredients, and there is no cat version, so cat owners are back to the Renue chew or to a multi-species product like the La Petite Labs Hollywood Elixir. A published dose is not a published result, either. Zesty Paws has no lifespan trial behind it any more than Renue does.
What the NMN evidence actually says
Here is the careful version, because this category invites overreach. NAD is a coenzyme central to cellular energy and repair, and it declines with age across species. Precursors like NMN and nicotinamide riboside are studied as a way to support NAD levels, and the human and rodent research is genuinely interesting. That is where the confident part stops.
Dog and cat specific evidence is early. There is no published trial demonstrating that either Renue pet chew does anything measurable, and there is no evidence that any NAD precursor extends a dog's or a cat's lifespan. The closest thing to real data in this category belongs to a different product: Leap Years is the one pet longevity product here with a published placebo-controlled trial behind it, and even that is a single trial in adult dogs rather than settled science.
So treat all of this as an early-stage bet on a plausible mechanism, not as care. Talk to your veterinarian before adding any supplement to an aging animal's routine, especially if there is an existing condition or a prescription in the picture, and bring the label with you. With the Renue dog chew there are nine actives on it, which is nine chances for an interaction with something your dog already takes.
How to choose
- Your senior dog would benefit from joint-formula ingredients anyway: the dog chews do both jobs in one daily chew, and the NMN costs less per milligram than buying an NAD precursor on its own.
- Your dog already takes glucosamine: do not stack blindly. Either switch rather than add, or use a single-ingredient product like Zesty Paws, and confirm the plan with your vet.
- You have a cat: the cat chews are one of very few NAD precursor products formulated for one, but go in knowing the per-milligram price is ordinary.
- Your animal reacts to seafood protein: neither of these works. The dog label states it contains shellfish and fish, the cat label states it contains fish.
- You want the most research behind the product: Leap Years is the only pet longevity option here with a published placebo-controlled trial.
- Your dog is over 80 lb: run the math before subscribing. Three chews a day is about $52 a month and empties a jar every 20 days, which changes the value story considerably.
Bottom line
Renue publishes its doses, and the doses are what should decide this. For dogs, 77 mg of NMN at $0.58 a chew is the cheapest NAD precursor on this shelf, about 55 percent below the per-milligram cost of the capsule alternative, with the caveat that you are also buying a 250 mg glucosamine formula whether you wanted one or not. For cats, 35 mg at the same $0.58 buys no per-milligram advantage at all. The cat version earns its place because almost nothing else on the market is formulated for a cat, and that is a thinner reason to buy than the dog version has. Check the allergen line, check what your animal already takes, and make the call with your veterinarian rather than from a product page.
- Ryan, Founder
How much NMN is in a Renue pet chew?
77 mg per chew in the dog version and 35 mg in the cat version. Both come from the PRODUCT FACTS panel, which Renue publishes as an image in the product gallery rather than as page text. At $0.58 a chew that is about $0.0076 per milligram for dogs and $0.0166 for cats, so only the dog version is cheap per milligram.
What do the Renue pet chews cost per day?
Both jars are $34.95 for 60 chews (verified 2026-08-06), which is $0.58 per chew. Dogs take 1 chew up to 40 lb, 2 chews from 41 to 80 lb, and 3 above 80 lb, so $0.58, $1.17, or $1.75 a day. Cats take 1 chew up to 10 lb and 2 above, so $0.58 or $1.17 a day.
Renue pet chews or Zesty Paws Healthy Aging?
For dogs, Renue is the better value: $0.0076 per mg of NMN against $0.0167 per mg of Niagen, both verified 2026-08-06. But Renue's dog chew is also a joint formula with 250 mg of glucosamine, so if you want an NAD precursor on its own, Zesty Paws is the cleaner buy. Note the two use different molecules.
Is there proof NMN helps dogs or cats live longer?
No. NAD precursor research in humans and rodents is interesting, but dog and cat specific evidence is early and no supplement has been shown to extend a pet's lifespan. Leap Years is the one product in this category with a published placebo-controlled trial behind it, and that is a single trial in adult dogs. Ask your veterinarian first.
Can I give my dog the cat chews, or the reverse?
No. They are different formulas, not different sizes. The dog chew lists nine actives at 637 mg including 250 mg of glucosamine and 77 mg of NMN. The cat chew lists two, 35 mg of NMN and 25 mg of fish oil. The dog label also states it contains shellfish. Buy the version for your species.
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