The best at-home blood test of 2026
Function vs Mito vs InsideTracker vs SiPhox vs HealthLabs, head-to-head on collection method, biomarker count, price, and what is actually included. Five ways to get serious bloodwork without a doctor visit, ranked honestly.
Read the collection column first. Of the comprehensive panels here, only SiPhox Health is self-collected at home. Function, InsideTracker and HealthLabs all send you to a Quest or Labcorp site for a draw by a phlebotomist. Mito draws at Quest, Labcorp or BioReference, will send a phlebotomist to you for a flat $99 in most US states, and also sells mail-back self-collection kits. They are excellent tests and two of them run far deeper panels, but if your reason for searching is that you do not want to go to a lab, the comprehensive field narrows to one.
Lifespan Vault earns an affiliate commission when you buy through links on this page, at no extra cost to you. It does not change our rankings or our verdicts.
- Best if you do not want to sit for a phlebotomist: SiPhox Health, $124 for the base Start Testing kit plus shipping (verified 2026-08-21), is the only service on this page you collect yourself: an upper-arm EasyDraw device with no finger prick, mailed back for up to 60 biomarkers in about 7 to 10 days. It is HSA and FSA eligible, and it is testing and insight only, not a prescribing relationship.
- Best if you want the widest panel at one fixed annual price: Function Health, $365 a year (verified 2026-06-19), runs 160+ lab tests twice a year with AI insights and clinician review, which is the deepest panel in this comparison. Collection is a venous draw at the Quest network, so it suits a buyer who will sit for a draw in exchange for the breadth.
- Best if you already have bloodwork to upload: Mito Health sells one-time panels at member pricing of $89.61 for the 117-marker Essential and $198.69 for the 138-marker Core, rising to $278.30 for Core at the non-member price (verified 2026-09-15), and lets members upload past labs so your trend line starts from bloodwork you already have. Budget the optional $9 a month membership and a lab draw fee, which is itemized at checkout. Prices and counts vary: New Jersey, New York and Rhode Island run through BioReference at higher prices, and the count reflects the sex-specific panel you select.
- Best if you want to be told what to do, not just what your numbers are: InsideTracker runs $199 for the Foundation base up to $647 for the fullest Ultimate variant (verified 2026-07-09), pairing 48 Ultimate biomarkers with specific food, exercise and supplement recommendations, plus a DNA Kit at $249. Every collection path is a phlebotomist draw, in a lab or mobile, so it is not an at-home test.
- Best if you already know the one marker you need: HealthLabs.com runs $59 to $459 a test (verified 2026-07-18), with Vitamin D at $59 and a Comprehensive Health Panel at $99, ordered online with no doctor visit, drawn at Quest or LabCorp and back in 1 to 3 business days. There is no AI layer and no clinician review, and it is not sold in New York.
We earn affiliate commission on some of the tests here (Mito Health, SiPhox, and HealthLabs are live partners). Function Health and InsideTracker pay us nothing and still made the list. Rankings reflect biomarker depth, collection method, cadence, evidence fit, and value, and we name who each one is wrong for.
The five at-home blood tests, compared
| Spec | Function Health | Mito Health | InsideTracker | SiPhox Health | HealthLabs.com |
|---|---|---|---|---|---|
| Price (verified) | $365/yr (verified 2026-06-19) | From $89.61 member, Core $198.69 (verified 2026-09-15) | $199-$647/test (verified 2026-07-09) | $124 base kit plus shipping (verified 2026-08-21) | $59-$459/test (verified 2026-07-18) |
| Biomarkers | 160+ lab tests | 100+ (Essential 117, Core 138) | 48 (Ultimate) | Up to 60 | Single to 100+ |
| Cadence | 2x/year included | One-time panels, optional $9/mo membership | Single test or annual | One-off or membership | A la carte, anytime |
| Collection | Quest draw (paid home visit optional) | Quest, Labcorp or BioReference draw, at-home phlebotomist $99, or mail-back kit | Lab or mobile phlebotomist draw | At-home, self-collected | Quest / LabCorp draw |
| AI insights | Yes | Yes, personalized plans | Yes, action-specific | Yes, action plan | No, raw values |
| Clinician review | Yes | Clinician-reviewed; 1:1 consult $39 member add-on | No (algorithm) | No (insight only) | No (you interpret) |
| Results speed | 5-10 days | Varies by test; shown per test before you buy | Not verified | ~7-10 days | 1-3 days |
| HSA/FSA | Varies by plan | Yes (Flex) | Varies by plan | Yes | Yes |
| Best for | 160+ tests twice a year at $365, if a Quest draw is acceptable | Uploading past bloodwork (a member feature); Essential 117 markers at $89.61 | Explicit food and exercise actions; Foundation from $199, 48-marker Ultimate from $340 | Quarterly testing with no lab visit; base kit $124 | One known marker back in 1-3 days; Vitamin D $59 |
Prices and specs are pulled from our product catalog and verified against each brand's own site. The five services were verified on five different dates, so each price carries its own date rather than one blanket date for the page. Tiers and pricing shift; confirm current pricing before you buy.
Breadth, collection, and the habit you keep
At-home blood testing splits into two real categories, and most buyers conflate them. The first is the comprehensive annual panel: a deep, one-or-twice-a-year snapshot of 100 to 160+ markers with AI insights and clinician review. Function Health and Mito Health own this lane. The second is frequent, low-friction check-ins between those deep draws, where a needle-free kit you complete at your kitchen table matters more than raw marker count. That is SiPhox. InsideTracker sits in between, trading breadth for the most explicit do-this-next guidance, and HealthLabs is the à la carte answer when you already know the single test you want.
The longevity-useful signal is the trend, not the single reading. Most markers move on a weeks-to-months timescale, which is why two comprehensive draws a year is the consensus cadence and why a cheap, easy kit for the quarters in between is genuinely valuable. The other honest point: a blood test measures, it does not treat. If a marker comes back off, you still need a clinician to act on it. Buy the test that fits the gap in your stack, then make sure you have a plan for what the numbers tell you.
Want one deep panel done right: Function Health. Want past-lab upload and a biological-age readout at the lowest cost to enter: Mito Health. Want explicit food and exercise actions: InsideTracker. Want a true no-needle kit you run often: SiPhox. Want one specific test, fast and cheap: HealthLabs.
Five at-home blood tests worth your money
Function Health - the deepest panel at a fixed price
$365/yr (verified 2026-06-19) · 160+ lab tests · 2x/year · AI insights + clinician review · Quest network draw
The one we steer most buyers to. Function took the $5,000 executive physical and turned it into a $365/year membership, and made it better: 160+ lab tests run twice a year, plotted as trends instead of one-off numbers, with AI insights flagging what changed and clinician review on anything abnormal. The panel goes deep where primary care stops, covering advanced lipid fractions, hormones, heavy metals, and cancer-relevant screens. The draw is an in-person venous collection at the Quest network, which keeps sample quality controlled. It is a data-and-insight layer, not a prescriber, so pair it with a clinician for anything that needs action. For breadth, cadence, and value in one membership, nothing here beats it.
Mito Health - the same playbook, with past-lab upload and biological age
Panels from $89.61 member, Core $198.69 (verified 2026-09-15) · 117 to 138 biomarkers · Biological age · Past-lab upload · Optional $9/mo membership · HSA/FSA via Flex
Mito runs Function's playbook far cheaper to enter (a one-time Core panel at $198.69 member, or Essential at $89.61, against $365 a year), so the decision is price and features together: 117 biomarkers on Essential and 138 on Core, AI-driven personalized action plans, a biological-age readout, and a clinician-reviewed result. The standout difference is past-lab upload. Members can upload historical bloodwork from a PCP or a prior platform so each biomarker trends over time, rather than spending your first year building a baseline. Mito also offers genetics and gut-microbiome add-ons that Function does not, steps up to Pro at $324.47 member ($454.40 non-member) for 166 markers weighted to heart health (28), blood health (50), hormones (15), energy and metabolism (19) and a 27-marker urine panel, and adding heavy metals, then to Ultra at $1,506.98 member ($1,912.40 non-member) for 178 markers with Galleri multi-cancer early detection plus an at-home gut-microbiome kit, and is HSA/FSA eligible via Flex. Two costs sit outside the panel price: a 1:1 clinician consult is $39 member or $99 otherwise, and the lab draw fee is itemized at checkout. Prices and biomarker counts vary: New Jersey, New York and Rhode Island run through BioReference at higher prices, where Core is $463.62 member and $649.23 non-member, and counts reflect the sex-specific panel selected at checkout. Galleri is not sold in New York, New Jersey or Rhode Island, and Rhode Island has no Mito lab location, so buyers there visit a lab in a neighbouring state. Collection is a blood draw at Quest, Labcorp or BioReference, or an at-home phlebotomist visit for a flat $99 in most US states, with mail-back kits and scans also available. The trades vs Function: one draw per panel (Function includes two a year), a narrower panel on Essential and Core (Function runs 160+), and a shorter US operating history (Mito made the US its primary home in January 2025). All Mito figures verified 2026-09-15. If past-lab upload or biological age matters to you, it is the pick.
InsideTracker Ultimate - data paired with explicit next steps
$199 Foundation base to $647 Ultimate (verified 2026-07-09) · 48 biomarkers (Ultimate) · DNA Kit $249 · Lab or mobile phlebotomist draw
The original blood-test-plus-AI-advice platform, doing this since 2009 as MIT-spinout science applied to athlete bloodwork. The entry plan is Foundation at $199 base; the Ultimate plan is variant-priced from $340 for the in-lab blood draw up to $647 with a mobile draw, InnerAge and estradiol/progesterone added (verified 2026-07-09). Ultimate tests 48 biomarkers, fewer than Function or Mito, but goes deeper on actionability: every result comes with specific food, exercise, and supplement recommendations tied to your individual numbers, plus DNA-informed adjustments if you add the $249 DNA Kit. Focus panels run $99 to $149. It also accepts existing lab uploads for free, so you can run the recommendation engine on labs your doctor already ordered. Where Function and Mito tell you what your numbers are, InsideTracker tells you what to do about them. Buy it for the cleaner app and explicit guidance; skip it if you want maximum marker coverage at the lowest cost.
SiPhox Health - the truly at-home, no-needle draw
$124 base Start Testing kit plus shipping (verified 2026-08-21) · Up to 60 biomarkers · At-home EasyDraw, no finger prick · AI action plan · HSA/FSA
The lowest-friction way to actually test as often as longevity tracking wants you to. You collect a small sample at home with the EasyDraw device (upper arm, no finger prick), mail it back, and get results across up to 60 markers in about 7-10 days, with an AI summary and a personalized action plan. It trades the breadth of the 100+ panels for convenience and price: the needle-free collection and a $124 entry price plus shipping make quarterly testing realistic, which is where biomarker tracking earns its keep. SiPhox repriced in 2026, so the older $99 to $189 band no longer appears on its site. It is HSA/FSA eligible, and membership plans for recurring testing exist, though their current prices sit behind the checkout flow so we do not quote them. The honest framing: it is testing and insight, not a prescribing relationship. The clean stack is one comprehensive annual panel plus SiPhox for cheaper check-ins between draws.
HealthLabs.com - a la carte testing without the wait
$59-$459 per test (verified 2026-07-18) · Single marker to 100+ panels · Quest + LabCorp · Results in 1-3 days · HSA/FSA
The shortcut when you know the exact test you want and do not want to wait three weeks for a doctor's appointment to order it. Order online, walk into the nearest Quest or LabCorp location, and results land in 1-3 days, faster than the membership platforms because there is no batch processing. The prices we checked on 2026-07-18 are Vitamin D at $59, the Comprehensive Health Panel at $99 and Testosterone Free plus Total at $99; HealthLabs lists a wider a la carte menu spanning roughly $24 to $459, and its own Live Price Guarantee can undercut a fixed quote. Assemble your own panel up to comprehensive scope if a single test is not enough. There is no AI layer, no trend visualization, and no clinician review: you get the raw values and interpret them yourself or share them with your own clinician. For buyers running protocols their PCP will not order for, or anyone comfortable reading their own labs, that is exactly the right trade. It is HSA/FSA eligible and available in most states (not New York).
The one-paragraph answer
If your reason for searching is that you do not want to go to a lab, the answer is SiPhox Health: $124 for the base Start Testing kit plus shipping (verified 2026-08-21), collected by you at home with an upper-arm device and mailed back. It is the only service here that works that way. If you are willing to sit for a draw, the panels get much deeper: Function Health runs 160+ lab tests twice a year for $365 (verified 2026-06-19) with AI insights and clinician review, and Mito Health runs 117 to 178 biomarkers by panel as one-time member panels from $89.61 (verified 2026-09-15), adds past-lab upload and a biological-age readout, and is HSA/FSA eligible. Want explicit food and exercise actions instead of raw data? InsideTracker runs $199 for the Foundation base up to $647 for the fullest Ultimate variant (verified 2026-07-09), though note it is a phlebotomist draw too. For single markers on demand, HealthLabs.com runs $59 to $459 a test, with Vitamin D at $59 (verified 2026-07-18). For the wider platform picture, see our best diagnostic platform guide.
A blood test is only worth it if you act on it. Pick the option that fits the gap in your stack, commit to a twice-a-year cadence for the comprehensive panel, and have a clinician relationship ready for anything that comes back off. The cheapest mistake in this category is paying for data you never use.
At-home blood test buyer's questions
Where should I buy an at-home blood test?
Buy direct from the brand. That is where the warranty is cleanest, where the current price is authoritative, and where sales show up first, which is why every link on this page goes to the brand store rather than a marketplace listing. Marketplace resellers of an at-home blood test routinely lag on price and muddy the warranty chain. Every price here is checked against the brand's own store and dated, for example the SiPhox At-Home Biomarker Test at $124, verified 2026-08-21.
What is the best at-home blood test overall?
If at-home means you never leave the house, it is SiPhox Health, $124 for the base Start Testing kit plus shipping (verified 2026-08-21): you collect the sample yourself with an upper-arm device and mail it back. Function Health (160+ tests, $365/yr) and Mito Health (117 to 178 markers by panel, one-time panels from $89.61) are the deeper panels and the better value per marker. Function sends you to a Quest site for a phlebotomist draw. Mito draws at Quest, Labcorp or BioReference for its comprehensive panels, and separately sells at-home mail-back kits and a $99 at-home phlebotomist visit. For the deep panels, both mean a professional draw.
Function Health vs Mito Health: which one?
Same playbook, different positioning. Function ($365/yr, verified 2026-06-19) runs 160+ lab tests twice a year with AI insights and clinician review, and has the longer track record and larger community. Mito sells panels as one-time purchases from $89.61 (Essential, 117 markers) or $198.69 (Core, 138 markers), with an optional $9/mo membership (verified 2026-09-15). Members can upload past bloodwork so each biomarker trends over time, and it offers genetics and gut-microbiome add-ons Function does not. The comparison is no longer a price tie: Mito is far cheaper to enter and asks for no annual commitment, while Function answers with a wider panel and two draws bundled into the year. For a first comprehensive panel, Mito is the lower-cost, lower-friction way in. If you are already in Function, do not migrate.
Function vs InsideTracker: which is better?
Function tests far more markers (160+ vs InsideTracker Ultimate at 48) and bundles two draws a year into $365 (verified 2026-06-19). InsideTracker runs $199 for the Foundation base up to $647 for the fullest Ultimate variant (verified 2026-07-09) and trades breadth for action: every result comes with specific food, exercise, and supplement recommendations, plus an optional DNA Kit at $249. Buy Function for maximum data at a fixed price. Buy InsideTracker if you want explicit do-this guidance and a cleaner app, and you do not want to interpret raw labs yourself.
Is an at-home blood test as accurate as a lab draw?
The analysis is. Every platform here runs samples through CLIA-certified labs, so the assay quality matches a clinic draw. The variable is collection. Function, InsideTracker and HealthLabs default to an in-person draw at Quest or LabCorp for their comprehensive panels, and Mito draws at Quest, Labcorp or BioReference or via a $99 at-home phlebotomist visit in most US states, which keeps collection controlled. SiPhox uses an at-home upper-arm device (no finger prick) that is convenient and reliable for most markers, though venous draw remains the gold standard for a few hormones and lipid fractions.
Do I need a doctor to order an at-home blood test?
No. All five options handle the physician order for you. Function, InsideTracker and SiPhox include the requisition in the membership or kit, and Mito has every order reviewed and signed by a Mito-network physician with no membership, referral or existing PCP required. HealthLabs provides the ordering physician as part of its direct-to-consumer model, so you order online and walk into Quest or LabCorp. Availability varies by state (HealthLabs is not available in New York, for example), so confirm before you buy.
How often should I test my biomarkers?
Twice a year is the consensus cadence for comprehensive panels, which is why Function builds two draws into its annual price (Mito sells panels individually, so you choose your own cadence). Most markers shift on a weeks-to-months timescale, so monthly testing is wasted spend and annual is too sparse to catch trends. If you are running an aggressive protocol, quarterly is defensible, and a low-friction kit like SiPhox makes that realistic and affordable between your comprehensive draws.
What is the cheapest way to get an at-home blood test?
For a single, specific marker, HealthLabs.com is the cheapest path: Vitamin D is $59 and results land in 1-3 days (verified 2026-07-18). For an entry-level multi-marker at-home kit, SiPhox is $124 for the base Start Testing kit plus shipping (verified 2026-08-21). For a comprehensive 100+ marker panel, Mito Core at $198.69 as a one-time member purchase is the lowest credible price (verified 2026-09-15), well under Function at $365 a year. Cheapest-per-marker for a deep panel goes to Mito and Function; cheapest single test goes to HealthLabs.
Which at-home blood test is HSA/FSA eligible?
Mito Health, SiPhox Health, and HealthLabs are all HSA/FSA eligible, so the saving depends on your marginal rate. Mito runs HSA/FSA through Flex and states net savings of 30 to 40 percent depending on your bracket. Confirm eligibility with your own plan administrator before buying, since employer-sponsored FSAs can set rules beyond the IRS guidelines.
Can an at-home blood test treat anything or prescribe medication?
No. All five are testing and insight tools, not prescribing relationships. They tell you what your numbers are doing and, in most cases, suggest changes. If a marker comes back abnormal, you still see a clinician to act on it. For active hormone, peptide, or GLP-1 prescriptions, pair your test with a prescribing provider rather than expecting the test to manage treatment.
This guide was researched and written by the editorial team at Lifespan Vault. We ranked each at-home blood test using verified pricing, biomarker count, testing cadence, collection method, AI and clinician features, results speed, HSA/FSA eligibility, and buyer fit. Prices and specs are pulled from our product catalog and verified against manufacturer pages; pricing is dated and may shift, and we update verified-at dates on individual product pages. Lifespan Vault may earn affiliate commission on outbound links: Mito Health, SiPhox Health, and HealthLabs are current affiliate partners, while Function Health and InsideTracker are listed for editorial completeness with direct links and no commission. Rankings are not for sale, and disclosures appear on every product page. For our full review process, see methodology / test protocol.
Related guides
- Best diagnostic platform 2026 - Mito vs Function vs InsideTracker vs Lifeforce, the membership view
- Best longevity wearables 2026 - Oura, WHOOP, Ultrahuman, Apple Watch, Garmin compared
- Best NMN supplements 2026 - what to act on once your labs are in
- SiPhox Health review - the no-needle at-home kit in depth
- Mito Health review - the past-lab-upload comprehensive panel in depth
Where to buy an at-home blood test
Direct links to the picks above. We earn a commission on some of these at no cost to you, and it never affects how anything is ranked. Picks without a link are ones we have no commercial relationship with.
Prefer to shop by who you are rather than by category? Try our buyer-intent collections.
Deep dives in this cluster
The Longevity Gear Buyer's Checklist
The specs that actually decide whether a sauna, cold plunge, red light panel, or smart ring is worth it, plus the real price range for each. Get the free PDF, plus one weekly email on the gear worth buying.